WACO, Texas - Odyssey Sims scored 18 of her 24 points in the first half and No. 6 Baylor coasted to its ninth straight win, beating Iowa State 89-51 Wednesday night.
Sims, the nation's leading scorer, made nine of 13 from the field and pushed her season total on 3-pointers to 80 by going 6 of 8 from long range.
The Lady Bears (23-3, 13-1 Big 12), who have their highest ranking of the season, took control with a 10-1 run midway through the first half on the way to their 34th straight conference home win.
Freshman Seanna Johnson scored 12 points to lead the Cyclones (17-8, 6-8), who haven't won two straight games since a 14-0 start capped by a 92-43 win over Texas Tech that put them at 3-0 in the Big 12.
It was the first of two meetings between the teams in the final five games of the regular season and the first since Baylor beat Iowa State 75-47 in the Big 12 tournament championship game last season.
Baylor frustrated Hallie Christofferson, the No. 2 scorer in the Big 12 behind Sims, with a variety of post defenders. She finished with 10 points but made just two of six from the field, even missing a shot from right in front of the basket after a steal in the backcourt.
The Cyclones let the game get away with 14 turnovers in the first half, including three straight when Baylor pushed a 26-17 lead to 33-17 and forced Iowa State coach Bill Fennelly to call two timeouts in less than a minute.
Imani Wright scored on a layup after the first miscue, and Sims hit a 3-pointer in transition after the second. Sims then stole a pass by Jadda Buckley for a breakaway layup.
The Cyclones finished with 19 turnovers - three off their season high - and the Lady Bears had a 20-0 edge in points off turnovers.
Sims had four steals to go with nine assists and five rebounds before coming out with Baylor leading by 35 with 8:01 remaining. She broke Emily Niemann's 10-year-old school record of 75 3-pointers with a shot that put the Lady Bears up 14-10.
Makenzie Robertson, the daughter of Baylor coach Kim Mulkey, hit three 3-pointers in the five 5 minutes of the second half to help the Lady Bears push their lead to 56-27.
Robertson made all three of her 3-pointers and finished with 11 points, and freshman Nina Davis had 11 points and six rebounds.
The Lady Bears held another opponent to less than 50 percent shooting. They've let just one team get above that mark in the past 279 games. The Cyclones shot 34 percent and were 3 of 25 from 3-point range.