ap photo The bipartisan group of Senate negotiators speak to reporters just after a vote to start work on a nearly $1 trillion bipartisan infrastructure package, at the Capitol in Washington, Wednesday, July 28, 2021. From left are Sen. Lisa Murkowski, R-Alaska, Sen. Susan Collins, R-Maine, Sen. Rob Portman, R-Ohio, Sen. Kyrsten Sinema, D-Ariz., Sen. Joe Manchin, D-W.Va., and Sen. Jeanne Shaheen, D-N.H., Google delays return to office, mandates vaccines.

WASHINGTON — The Senate voted Wednesday night to begin work on a nearly $1 trillion national infrastructure plan, acting with sudden speed after weeks of fits and starts once the White House and a bipartisan group of senators agreed on major provisions of the package that’s key to President Joe Biden’s agenda.

Biden welcomed the accord as one that would show America can “do big things.” It includes the most significant long-term investments in nearly a century, he said, on par with building the transcontinental railroad or the Interstate highway system.

“This deal signals to the world that our democracy can function,” Biden said ahead of the vote. “We will once again transform America and propel us into the future.”

After weeks of stop-and-go negotiations, the rare bipartisan showing on a 67-32 vote to start formal Senate consideration showed the high interest among senators in the infrastructure package. But it’s unclear if enough Republicans will eventually join Democrats to support final passage.

Senate rules require 60 votes in the evenly split 50-50 chamber to proceed for consideration and ultimately pass this bill, meaning support from both parties.

The outcome will set the stage for the next debate over Biden’s much more ambitious $3.5 trillion spending package, a strictly partisan pursuit of far-reaching programs and services including child care, tax breaks and health care that touch almost every corner of American life. Republicans strongly oppose that bill, which would require a simple majority, and may try to stop both.

Lead GOP negotiator Sen. Rob Portman of Ohio announced the bipartisan group’s agreement on the $1 trillion package earlier Wednesday at the Capitol, flanked by four other Republican senators who had been in talks with Democrats and the White House.

After voting, Portman said the outcome showed that bipartisanship in Washington can work and he believed GOP support would only grow. “That’s pretty darn good for a start,” he said.

That group had labored with the White House to salvage the deal, a first part of Biden’s big infrastructure agenda. Swelling to more than 700 pages, the bill includes $550 billion in new spending for public works projects.

In all, 17 Republican senators joined the Democrats in voting to launch the debate, but most remained skeptical. The GOP senators were given a thick binder of briefing materials during a private lunch, but they asked many questions and wanted more details.

According to a 57-page GOP summary obtained by The Associated Press, the five-year spending package would be paid for by tapping $205 billion in unspent COVID-19 relief aid and $53 billion in unemployment insurance aid some states have halted. It also relies on economic growth to bring in $56 billion, and other measures.

Giving Wednesday night’s vote a boost, Senate GOP leader Mitch McConnell announced late in the day he would vote to proceed, though whether he will support the final bill remains uncertain. The Republican negotiators met with McConnell earlier Wednesday and Portman said the leader “all along has been encouraging our efforts.”

Sen. Kyrsten Sinema of Arizona, a lead Democratic negotiator who talks often with Republicans also spoke with Biden on Wednesday and said the she hoped the results showed “our government can work.”

Democrats, who have slim control of the House and Senate, face a timeline to act on what would be some of the most substantial pieces of legislation in years.

Filling in the details has become a month-long exercise ever since a bipartisan group of senators struck an agreement with Biden in June over the broad framework.