PORTLAND, Ore. — Freshman Tamin Lipsey made four free throws, his only points of the game, in the last 20 seconds of overtime, when he also had a key steal, and the Iowa State men’s basketball team defeated Villanova 81-79 in the Phil Knight Invitational on Thursday.

The Cyclones (4-0), who face top-ranked North Carolina in the semifinals on Friday, opened the second half with a 17-1 run to take a 51-35 lead but the Wildcats (2-3), who face Portland, scored the last seven points of regulation.

Caleb Grill hit a 3-pointer to open the overtime and Villanova, which hadn’t been even since a 30-30 tie and at the end of regulation when Iowa State’s Jaren Holmes missed a contested jumper at the buzzer, never caught up.

Gabe Kalscheur, who led Iowa State with 25 points, had five points in overtime and Osun Osunniyi, who had 17, powered in for a layup with 42.3 seconds to go for a 77-74 lead. That’s when Lipsey made a good read to intercept a cross-court pass. He was cool at the line after being fouled. Then the Cycles got the ball into him with 9.5 seconds to go to ice it after Caleb Daniels scored inside to pull Villanova within 79-76.

Daniels, who led the Wildcats with 25 points, seven rebounds and seven assists, hit a 3-pointer with two seconds to play. Eric Dixon had 21 points and 10 rebounds for Villanova.

Iowa St. 81, Villanova 79, OT

IOWA ST. (4-0) — Kunc 2-6 0-0 6, Osunniyi 8-10 1-1 17, Grill 1-5 2-2 5, Holmes 5-15 2-3 12, Lipsey 0-0 4-4 4, Kalscheur 8-19 2-2 23, Jones 4-7 2-3 10, Ward 2-3 0-0 4, Watson 0-1 0-0 0. TOTALS 30-66 13-15 81.

VILLANOVA (2-3) — Dixon 8-16 1-2 21, Slater 3-10 6-7 14, Arcidiacono 2-8 0-0 6, Daniels 6-12 10-12 25, Longino 2-6 2-2 7, Brizzi 1-1 1-2 3, Armstrong 0-2 0-0 0, Patterson 0-1 0-0 0, Hausen 1-1 0-0 3. TOTALS 23-57 20-25 79.

Halftime–34-34. 3-Point Goals–Iowa St. 8-28 (Kalscheur 5-15, Kunc 2-5, Grill 1-4, Osunniyi 0-1, Watson 0-1, Holmes 0-2), Villanova 13-36 (Dixon 4-9, Daniels 3-7, Slater 2-6, Arcidiacono 2-7, Hausen 1-1, Longino 1-4, Armstrong 0-2). Fouled Out–Kalscheur. Rebounds–Iowa St. 35 (Kunc 6), Villanova 33 (Dixon 10). Assists–Iowa St. 22 (Holmes 9), Villanova 17 (Daniels 7). Total Fouls–Iowa St. 23, Villanova 19.