AP PHOTO - San Francisco 49ers quarterback Brock Purdy speaks at a news conference after Monday night’s NFL game against the Baltimore Ravens in Santa Clara, Calif.

SANTA CLARA, Calif. — Brock Purdy’s storybook ride from final pick of the 2022 draft to most efficient quarterback in the NFL has featured very few on-field struggles.

That’s what made his four-interception performance in one of the most highly anticipated games of the season so glaring. How Purdy bounces back from the 33-19 loss to the Baltimore Ravens on Monday night will go a long way in determining how successful this season will ultimately be for the 49ers.

“I think it’s unbelievable how he’s played for the past two years,” defensive end Nick Bosa said. “Just being a young rookie last year, it seems like he’s immortal out there. But no one is immortal. He’s responded from not his best performance before and I think he will do that again.”

Purdy’s night got off to a bad start when he didn’t see safety Kyle Hamilton and threw an interception in the end zone on the first drive of the game for San Francisco (11-4).

A deflected pass off a cornerback blitz led to his second turnover and then a questionable decision to throw across his body over the middle on a play that already had a penalty on San Francisco led to the third interception.

He was then hit on a pass that was intercepted on the second drive of the third quarter, essentially sealing San Francisco’s fate.

“I just think the fact he’s played this long and never had a game like this is pretty unusual,” coach Kyle Shanahan said. “I think that’s the reality of the NFL. I’m not saying it’s bound to happen, but I wish he didn’t have as many picks. But like I said, I think one of them was one he’d really liked to have back. The other three I think were unfortunate.”

It was by far the worst game of Purdy’s 23 career starts in the regular season and playoffs. He had been on a near record-setting pace this season before the setback against one of the NFL’s top defenses.

But the loss doesn’t have to be crushing for San Francisco. The Niners can still clinch the No. 1 seed and a first-round bye with wins over Washington and the Rams the next two weeks.

“It’s easy to be riding the high and thinking you’re the man when things are going well, winning games and all that kind of stuff, and you don’t really see a whole lot of adversity in some games,” Purdy said. “This is the reality of the NFL.”